Nutshell of this article:
It’s Metronidazole, Loperamide (Immodium) and Rice/Hamburger feeding.

Disclaimer: I don’t like using Loperamide in kittens. It can make them really jittery. If their whiskers are “vibrating” you need to skip the “next” dose.

Immodium for Kids*
Specifically: IMODIUM® Anti-Diarrheal Oral Solution (liquid) Diarrhea Medicine For Children Ages 6 and Up
ACTUAL INGREDIENTS: Anhydrous citric acid, caramel color, D&C yellow no. 10, FD&C blue no. 1, flavor, glycerin, microcrystalline cellulose and carboxymethylcellulose sodium, propylene glycol, purified water, simethicone emulsion, sodium benzoate, sucralose, titanium dioxide, xanthan gum

Strength is: Per 7.5 mL – Loperamide HCl 1 mg – Anti-diarrheal
Dose for a cat is: (Low dose) 0.05 mg/lb

Example: 3 pound kitten: 0.15mg

Dosing interval: Up to three times a day. I would recommend limiting it to 2x daily 12 hours apart with the following rule:
If there’s been no poop for 12 hours, skip the dose.
If there’s been a loose stool in the last 12 hours, dose with the Immodium and ‘reset the clock’ for the 12 hour interval.

i.e. She’s supposed to get a dose at 6pm. But she has a really loose stool at 4pm. Give the 6pm dose of Immodium at 4pm and then add 12 hours for the next dose. If this causes the need for three doses in 24 hours, fine.
Do not use Loperamide more than 3 days in kittens.

So Loperamide for Kids = 3lb kitten = 0.60 ml by mouth (Need a 1.0 ml syringe) (Fill slightly more than halfway)

* To make “Immodium for Kids” at home: (For kittens ha ha ha)
Crush 1 (“adult”) Immodium tablet (2mg per tablet) in 15cc Karo Syrup.
Give 0.2cc per 1lb up to three times a day, as described above.


Feed a mixture of white rice and hamburger with fat removed.
A mixture of two parts rice and one part boiled hamburger with fat removed.
Mix one and a half cups of cooked white rice (or potato) with one half cup of low fat cottage cheese. Some cats prefer pasta to rice.
Live culture yogurt may help control diarrhea in cat . Dose range is from 2 to 5ml with each meal. This is an attempt to add beneficial bacteria to the digestive tract.

I also don’t like Metronidazole in kittens, either but sometimes, what are ya gonna do?

Dose for a 3 pound kitten is 7mg – 10mg
A Metronidazole tablet is 250mg each.
We need a 25th of that tablet oh my God.


Mix one crushed 250mg Metronidazole tablet in 5cc of Karo Syrup.
3lb kitten = Give 0.20 ml of this every 12 hours.

Author: Dr. Erik Johnson



Johnson Vet Services 2023